Discovery Diagnostics Laboratory Test Kits Diagnostic Equipment Distributor

Nanoduct™ Neonatal Sweat Analysis System
Early Cystic Fibrosis Diagnosis

Discovery Diagnostics, Canadian distributor for Wescor's Nanoduct Neonatal Sweat Analysis System for early laboratory diagnosis of cystic fibrosis.

Early diagnosis and treatment can significantly improve both the quality of life and the lifespan of children born with cystic fibrosis. The proven diagnostic effectiveness of analyzing electrolyte concentration in sweat makes it vital to perform this test as soon as possible after birth.

ELITech-Wescor has long been the leading innovator in the laboratory diagnosis of cystic fibrosis® with the Macroduct Sweat Collector and its companion, the Sweat-Chek™ Sweat Conductivity Analyzer.

GROUND BREAKING INNOVATION BASED ON PROVEN TECHNOLOGY
The Nanoduct Neonatal Sweat Analysis System combines and miniaturizes the proven collection and analysis technologies of Macroduct and Sweat-Chek to accommodate the tiny limbs of newborn infants, and provides reliable laboratory diagnosis of CF as soon as a newborn’s sweat glands are capable of producing sweat.

Innovative features of the Nanoduct System include the special electrode/sensor holders that are positioned on the patient’s limb before iontophoresis. The holders make electrode placement simple and secure. They also guarantee that the sensor collecting surface is perfectly registered with the stimulated skin area and attachment pressure is optimal when the sensor is attached.

Nanoduct incorporates the classic method of inducing sweat by pilocarpine iontophoresis. The pilocarpine is carried into the dermis of the patient from improved Pilogel® Iontophoretic Discs by a controlled DC electric current supplied by the Nanoduct System.

This is followed by continuous flow analysis of sweat electrolyte concentration using the unique conductivity sensor. Electrodes and the sensor are connected to the Nanoduct System via a single control cable.

The Nanoduct Neonatal Sweat Analysis System simplifies the sweat test and for the first time makes possible reliable laboratory diagnosis of CF in the first days of life.

CONTINUOUS-FLOW ANALYSIS OF ELECTROLYTE CONTENT
When the sensor is attached to the patient, the stimulated sweat emerging from the sweat glands is anaerobically directed into a microconductivity cell within the sensor. This provides a continuous display of the electrical conductivity in the freshly emerged sweat. Conductivity has been shown to be the equal of chloride in its ability to discriminate diagnostically between CF and non-CF subjects.

SEPARATE COLLECTION PHASE IS ELIMINATED Continuous-flow analysis while the sensor is on the limb, eliminates potential handling errors, saves laboratory time, and ensures accuracy by providing virtually infinite replications of the analysis on freshly excreted sweat. A further benefit: any inadvertent contamination of the sensor collecting surface will be dissipated before the final reading is displayed.

IMPROVED PILOGEL DISCS®
?Increased pilocarpine concentration
?Iontophoresis time reduced to only 2.5 minutes
?Buffered to prevent pH changes

Readout	128 x 64 LCD graphic display (non-backlit). Supports up to 8 lines of 18 characters or numerals, with multi-lingual support (English, French, German and Spanish
Sound	Alert and Alarm signals.
Keyboard	ON, OFF, SELECT and ENTER keys.
Electrode Connection	6-pin locking medical connector to mate with induction/conductivity cell cable
Serial Outputs	RS-232 (ASCII format) 9-pin D-sub male connector USB - device Type B receptacle.
Sweat Induction Control	Four AA Alkaline batteries (NEDA 15A, IEC, LR6) Typical solid state, over-curent circuit protection 3.0 VDC lithium coin cell for the real-time clock
Real-Time Clock	± 2 minutes per year (battery backed)
Operating Temperature	15 to 30 ° C (59-86 ° F
Storage Temperature	0 to 60 $deg; C (32 to 140 ° F)
Instrument (H x W X D)	7.5 x 5 x 2 in. (19.1 x 12.7 x 5.1 cm)
Weight	1.2 lb (0.5 kg)
Carrying Case	13x5 x 10.5 x 4 in (34x3 x 26.7 x 10.2 cm)
Sweat Analysis Conductivity Readout	mmol/L (equivalent CaCI)
Conductivity Range	30 to 200 mmol/L
Precision	CV < 1% from 285 to 150 mmol/L (equivalent NACI)
Initial Sweat Rate	0 to 50 g/m²/min
Calibration	Single-point automatic calibration at 80 mmoll/L (equivalent NACI) using the AC-081 Calibration Plate

Cat. No.	Item
NANODUCT 1030	NANODUCT Neonatal Sweat Analysis System
Accessories
AC-081	Calibration Standard Plate for Nanoduct
AC-111	Patient Simulator for Nanoduct
AC-113	Power Supply for AC-111
AC-115	Lab Report Software Utility Kit
Supplies for Nanoduct System
SS-043	Supply Kit for Nanoduct - 6 tests
SS-220 SS-231	Waste Pads (100) for AC-111
Repair/Replacement Parts for Nanoduct System
RP-238	Battery, lithium CR2025 3V
RP-343	s/n < *0477, Electrode Cable Set for Nanoduct
RP-347	Case Latch for Nanoduct
RP-349	s/n >= *0477, Main PCBA (Dealers Only), Nanoduct
RP-350	Cleaning Adaptor for AC-111
RP-351	Tweezers
RP-352	Hemostat
RP-353	Attachment Strap Retainer Post, Nanoduct
RP-354	Electrode Strap, Small, Nanoduct
RP-355	Electrode Strap, Medium, Nanoduct
RP-356	Electrode Strap, Large, Nanoduct
RP-357	Pos (+) Red Holder for Sensor Cell, Nanoduct
RP-358	Neg (-) Black Holder for Sensor Cell, Nanoduct
RP-359	s/n >= *0477, Electrode Cable Set, Rd/Blk, Nano
RP-360	s/n >= *0477, Manual, instruct/srvc, Nanoduct
RP-361	Manual, instruction, for AC-111
Factory Service
FS-451	Nanoduct Calibration Plate Verification

Canadian Customers if you wish to speak to a sales representative or customer service, please call Toll Free within Canada: 1-888-883-9101. Outside Canada, click here for ordering information.

Downloadable Files:

Nanoduct Neonatal Sweat Analysis System Brochure
PDF Format (665 kb)

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Nanoduct Neonatal Sweat Analysis System Early Cystic Fibrosis Diagnosis Discovery Diagnostics, Canadian distributor for Wescor's Nanoduct Neonatal Sweat Analysis System Infant CF Diagnosis

Nanoduct™ Neonatal Sweat Analysis System Early Cystic Fibrosis Diagnosis

Nanoduct™ Neonatal Sweat Analysis System
Early Cystic Fibrosis Diagnosis