Platelet Aggregation Reagents
For all of your hemostasis reagent
needs, turn to Discovery Diagnostics, the Canadian distributor for
Helena Laboratories platelet aggregation reagents. From general coagulation
to specialized assays, We distribute Helena's top-quality reagents
including;
• ADP Reagent
• Collagen Reagent
• Epinephrine Reagent
• Arachidonic Acid
• Ristocetin (for Aggregation Assays)
• Ristocetin Cofactor Assay Kit
• Lyophilized Platelets
• Ristocetin Cofactor Abnormal 888 Control Plasma
| Cat.
No. |
Item |
| 5369 |
Platelet
Aggregation Kit
• ADP Reagent, 2 x 1 mL
• Collagen Reagent, 2 x 1 mL
• Epinephrine Reagent, 2 x 1 mL
The Platelet Aggregation Kit is used to identify normal
and abnormal platelet function, to quantitate platelet
response and to determine the patient's response to anti-platelet
drug therapy. The reagents are optimized for use with
the Helena PACKS-4, but may be used on any turbidometric
aggregometer of similar quality.
|
 |
| Cat.
No. |
Item |
| 5366 |
ADP
Reagent
• ADP, 2 x 1 mL
ADP is a lyophilized preparation of adenosine-5-diphosphate.
ADP is for use in routine platelet aggregation studies
for the evaluation of qualitative platelet function disorders.
The concentration of the reconstituted ADP reagent is
200 mM. |
 |
| Cat.
No. |
Item |
| 5368 |
Collagen
Reagent
• Collagen, 2 x 1 mL
The collagen reagent
is a clear, stabilized liquid reagent which is one of
the world's best collagen preparations. Collagen is for
use in routine platelet aggregation studies for the evaluation
of qualitative platelet function disorders. The concentration
of the collagen reagent (equine tendon) is 100 mg/mL.
|
 |
| Cat.
No. |
Item |
| 5367 |
Epinephrine
Reagent
• Epinephrine, 2 x 1 mL
Epinephrine is a lyophilized preparation of L-epinephrine
bitartrate. Epinephrine is for use in routine platelet
aggregation studies for evaluation of qualitative platelet
function disorders. After reconstitution, epinephrine
concentration is 548 mg/mL. |
 |
| Cat.
No. |
Item |
| 5364 |
Arachidonic
Acid
• Arachidonic Acid, 2 x 1 mL
Arachidonic Acid
is a lyophilized preparation of sodium arachidonate for
use in platelet aggregation studies of abnormal function,
especially dysfunction induced by aspirin and aspirin-containing
medications. |
 |
| Cat.
No. |
Item |
| 5199 |
Ristocetin
(for Aggregation Assays)
• Ristocetin, 10 x 0.5 mL
This Ristocetin is
for use in platelet aggregation studies for confirmation
of von Willebrand Disease (vWD) and Bernard-Soulier Syndrome.
Normal platelet-rich plasma exhibits a positive aggregation
response to the addition of ristocetin using a final concentration
of 12-15 mg/mL. The majority of vWD patients exhibit a
negative response to ristocetin as do Bernard-Soulier
patients.
|
 |
| Cat.
No. |
Item |
| 5370 |
Helena
Ristocetin Cofactor Assay Kit
• Ristocetin
Cofactor Kit, 50 tests
• Lyophilized Platelets, 4 x 5.0 mL
• Ristocetin Cofactor Abnormal Control,
2 x 0.5 mL
• S.A.R.P. Assayed Reference Plasma, 2
x 1.0 mL
• Helena Ristocetin - 10 mg/mL, 2 x 1.5
mL
• Tris-Buffered Saline, 1 x 35 mL
Ristocetin cofactor assays
measure the ability of von Willebrand factor (Ristocetin
cofactor) in the patient's plasma to agglutinate formalinized
platelets in the presence of ristocetin. Decreased levels
of ristocetin cofactor activity are associated with
von Willebrand Disease.
|
 |
| Cat.
No. |
Item |
5356
5371 |
Lyophilized
Platelets, 5 x 10 mL
Lyophilized Platelets, 5 x 5 mL
Lyophilized Platelets
are a standardized suspension of fixed platelets derived
from platelet concentrate. Lyophilized Platelets are for
use in the quantitation of ristocetin cofactor activity
in plasma. The platelets are lyophilized for stability.
Tris-Buffered Saline (Cat. No. 5365) should be used for
reconstitution. The concentration of the reconstituted
platelet suspension is approximately 200,000/mL. Platelets
in Cat. No. 5356 show a slower reaction rate.
|
 |
| Cat. No. |
Item |
| 5373 |
Ristocetin Cofactor Abnormal Control Plasma
• Ristocetin Cofactor Abnormal Control,
5 x 0.5 mL
The control is to
be used in the assay of ristocetin cofactor. It contains
citrated human plasma with a level of ristocetin cofactor
activity below 50%.
|
 |
| Cat. No. |
Item |
| 5372 |
Ristocetin - 10 mg/mL (for Ristocetin Cofactor Assays)
• Ristocetin - 10 mg/mL, 5 x 1.5 mL
The reagent is to
be used in the quantitative determination of ristocetin
cofactor activity. The ristocetin reagent is prepared
from Nocardia lurida and is used in the tests for von
Willebrand Disease and Bernard-Soulier Syndrome.
|
 |
| Cat.
No. |
Item |
| 5365 |
Tris-Buffered Saline
• Tris-Buffered Saline, 1 x 125 mL
Tris-Buffered Saline
is used for reconstitution and dilution of some of the
reagents used in platelet aggregation assays and ristocetin
cofactor assays. |
 |
Canadian Customers if you
wish to speak to a sales representative or customer service, please
call Toll Free within Canada: 1-888-883-9101. Outside Canada, click
here for ordering information.
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